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In that 10-week frame, I lost 10 pounds

Before taking Pepto-Bismol with Wegovy, you should: Consult your GP or prescribing clinician, particularly if symptoms are severe or persistent Check for contraindications to bismuth subsalicylate (such as aspirin/salicylate allergy, bleeding disorders, kidney problems, pregnancy, breastfeeding, or if under 16 years of age) Consider whether your symptoms might be better managed through Wegovy dose adjustment Avoid prolonged use of Pepto-Bismol without medical advice Be aware that bismuth can cause harmless darkening of stools and tongue, which should not be confused with bleeding If gastrointestinal symptoms are significantly impacting your quality of life, contact your healthcare provider rather than relying solely on over-the-counter remedies

Generally, these side effects tend to be most pronounced when you start taking semaglutide and when you increase your dose

Those experiencing nausea, vomiting, or diarrhea should be especially attentive to hydration status and may benefit from oral rehydration solutions containing electrolytes

Because that is unusually long compared with most medications, the drug accumulates across weeks rather than clearing between doses