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In addition, genes upregulated by smoking among apical epithelial cell types ( KRT8 high , mucus secretory, and ciliated) were enriched for mucus secretory cell markers, supporting an increase in the secretory activity of these cells (Fig
Money collected from personal income taxes is 53% of state revenues
Smoking now kills 480,000 Americans each year
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At first, we found that addition of an end-repair step to fill in 5 overhangs and detect base-editor-modified gDNA resulted in high background and detection of only a small fraction (20%) of previously validated off-target sites (Extended Data Fig
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