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Moreover, IL-1 can induce the accumulation of reactive oxygen species (ROS), through the expression of iNos

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Exclusion criteria were defined as follows: Known nutritional-, metabolism- or inflammation-related stressors Premature birth as a stressor Nutrition only described as a variable in the statistical model of a human cohort study (and not in main research question of study) Intervention with pharmacological extracts/molecules that are not typically nutrient-derived Studies that did not include non-stressed controls Only a structural or mechanistic outcome measure Reviews Considerations for interpretation of neurobehavioral outcomes in response to ES and nutritional intervention Throughout this review we will refrain from assigning positive or negative connotations concerning to neurobehavioral consequences of ES and nutritional interventions as these can be adaptive or maladaptive contingent on the specifics of environment and setting where these are expressed [19, 20]