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In case higher age contributes to elevated eCO levels, it could probably explain lower median eCO levels among these patients compared to those who reported smoking, as well as contribute to higher blood pressure in this group and more advanced coronary artery disease resulting in greater proportion patients presenting with MI as an index event

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Cocaine use can cause the blood vessels to constrict, causing lymphatic fluid to build up in the narrowed vessels, which can contribute to bloating or swelling