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However, the relatively low number of HHV-6 infected cells in brains of MS patients, as compared with encephalitis patients, suggests mechanisms other than direct cell destruction may be involved

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In addition, knocking down ACTL6A increased the expression levels of prostaglandin-endoperoxide synthase 2 (PTGS2) (Supplementary Fig 3b), which is a ferroptosis marker 30,46

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