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Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

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The CpG site cg04605617 was most significantly associated with QT interval prolongation [ (95%CI): 0.175 (0.13, 0.22), P = 1.82E-13] and mapped to the promoter region of the protein-coding gene Phospholipase A2 Group IIC ( PLA2G2C ) (chr1: 20,501,558) (Fig

We as clinicians have the responsibility to keep our eyes open for such clinical outliers, Oxnard says, because they may provide unique insights on a more deep biological level. References Couraud, S

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