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This table summarizes key epidemiologic and longitudinal cohort studies examining the relationship between cigarette smoking and multiple sclerosis (MS), including disease susceptibility, conversion from clinically isolated syndrome (CIS) to clinically definite MS, disability accumulation, and progression to secondary progressive disease

Louis shared a photo of himself and Steve Aoki performing their track Just Hold On at the X Factor final at the weekend and captioned the Instagram post: "Thank you for the incredible support :)" Louis had previously thanked his loved ones and fans for helping him through the live TV performance

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Just 14 percent of the people in either group hadn't smoked a cigarette in the previous week -- underscoring just how hard it is to kick the nicotine habit

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