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[63] In a November 2023 letter to Joe Biden, they claimed that their members made $23.7 billion in sales on menthol cigarettes and flavored cigars and another $10.7 billion in non-tobacco sales among these smoking customers during 2022

Though they are made to look like legitimate THC vaporizers, which heat up a solution of cannabis oil, these street vapes often contain othermore harmfulsubstances

While the aforementioned findings are primarily derived from preclinical models, such as CSE-treated animals or cells, they demonstrate the possibility of using natural products to intervene in COPD pathology by regulating macrophage metabolic imbalances