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Ozempic approved to reduce cardiovascular risk Ozempic (semaglutide 0.5 mg, 1 mg, and 2 mg) previously received FDA approval for cardiovascular health in people with type 2 diabetes after combined results from the SUSTAIN-6 and PIONEER-6 trials showed a 24% reduction in major adverse cardiac events (MACE) such as heart attack, stroke, and other cardiovascular-related deaths

Moreover, GLP-1 promotes neurogenesis by reducing inflammation and decreasing the expression of proinflammatory cytokines IL-6, IL-10, and microglial activation (25)

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