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Both Ozempic and Wegovy are powerful medicines and hence will require a prescription

Benefits appear mediated through weight reduction rather than direct anti-inflammatory effects on joints

I measure all of my patients eGFR but also UACR ratio because you wont know who might benefit from these therapies until you actually identify CKD. FLOW findings The FLOW trial enrolled 3,533 adults with type 2 diabetes and high-risk CKD on stable renin-angiotensin system (RAS) inhibitor therapy

This is the first trial to demonstrate cardiovascular benefit with a weight-management medication in people without diabetes

Once a protein is denatured, it does not un-denature