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Shields, a co-author of the study, deputy director of the Comprehensive Cancer Center at James Cancer Hospital and a professor at the Ohio State University

And when you have a large enough cohort, as we did in this study, we can see that theres a preference towards those stops in tumor suppressor proteins through the mutational processes. The study also identified other factors and processes responsible for creating large numbers of stop-gain mutations, which are also called nonsense mutations

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This dissolution of borders allows one to follow the piece as one would follow a path along a Moebius stripborders become recentered in the work as soon as the content of the piece comes back into focus

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