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In clinical trials, hair loss was reported in 4-5% of people using tirzepatide (Zepbound) compared to 1% on placebo

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According to the Phase 2 trial published in the New England Journal of Medicine , retatrutide achieved weight reductions up to 24.2% at 48 weeks , with projections nearing or exceeding 25% at full duration (Coskun et al., 2023)