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During the transition: Monitor blood glucose more frequently for the first 4 to 6 weeks Expect potential hypoglycemia risk if also taking insulin or sulfonylureas Your provider may need to adjust other diabetes medications A1C improvements may be more pronounced with tirzepatide The SURPASS clinical trials demonstrated that tirzepatide 15 mg reduced A1C by up to 2.58%, compared to semaglutide 1 mg which reduced A1C by 1.86%

Both OASIS 4 and the earlier OASIS 1 trial of oral semaglutide reported dysaesthesia

Do not pour unused medication down the drain or put it in household trash

Readers should consult their healthcare professional or pharmacist for the most current information on medication availability and treatment options.

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