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Interestingly, the addition of hGSTs results in major changes in the regioselectivity of GSH conjugation of the reactive clozapine metabolite, possibly due to the different active site geometries of hGSTs [33]

In general, available pharmacopeial methods commonly used in GMP settings for peptides primarily rely on IP-RPLC, often using nonMS-compatible ion-pairing reagents, with only a few methods employing more MS-compatible alternatives

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Ela desempenha um papel crucial no metabolismo energtico, transportando cidos graxos para dentro das mitocndrias as organelas das clulas que produzem energia

[DOI] [PubMed] [Google Scholar] 15.Zaidi M., Moonga B.S., Bevis P.J.R., Bascal Z.A., Breimer L.H