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Smoking is a leading cause of cancer because tobacco smoke many harmful substances, including over 50 carcinogens

There is conclusive evidence that, other than nicotine, the number, quantity, and characteristics of potentially toxic substances emitted from e-cigarettes are highly variable and depend on product characteristics (including device and e-liquid characteristics) and how the device is operated

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Fuel Early on, lighters used naphtha as fuel, but a change to butane occurred in the 1950s