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doi: 10.3389/fcdhc.2025.1720794 Received 09 October 2025 Accepted 03 November 2025 Published 24 November 2025 Volume 6 - 2025 Edited by Marilena Vitale, Federico II University Hospital, Italy Reviewed by Theodoros Androutsakos, National and Kapodistrian University of Athens, Greece Gianpaolo Zerbini, San Raffaele Hospital (IRCCS), Italy Giovanna DAbbronzo, Federico II University Hospital, Italy Updates Copyright 2025 Codella, Senesi and Luzi

On average, semaglutide GLP-1 injections achieve a 15% reduction in starting weight when used as part of a comprehensive weight loss plan

Rapid physiological changes : Significant weight loss and metabolic changes may affect some individuals' psychological wellbeing, particularly if changes occur quickly, though the evidence for this is limited

Theres also evidence suggesting that tesofensine can cure alcohol addiction via its ability to boost neurotransmitter levels: Tesofensine side effects are very uncommon and similar to other currently approved diet pills and weight loss medications

Wegovy typically lists between roughly $1,350 and $1,865 for a one-month supply, depending on dose and pen configuration