It also may have some benefits in reducing the risk of kidney disease in people with type 2 diabetes
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A 2024 systematic review of 38 animal and human studies found that GLP-1 medications significantly affect gut microbiota diversity and composition 2 : Liraglutide: promotes growth of beneficial genera linked to improved metabolic health Dulaglutide: increases Bacteroides, Akkermansia, and Ruminococcus, genera associated with better gut and metabolic outcomes Semaglutide: increases Akkermansia muciniphila , a beneficial bacterium, but may reduce overall microbial diversity
Its standout feature lies in being a non-injectable GLP-1 receptor agonist, simplifying treatment without the need for complex machinery