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All the statistical analyses were performed using GraphPad Prism 7 (GraphPad Software)

10.3389/fphys.2021.673341 91 GutowskaK.FormanowiczD.FormanowiczP

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Changes in daily smoking, the number of disease exacerbations, lung function indexes, patient-reported questionnaires (COPD Assessment TestCAT), and 6-min walk distance (6MWD) from baseline were assessed