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A GHRH analog (like CJC-1295 or Tesamorelin) tells the pituitary to make and get ready to release more GH it primes the tank

However, a key counterargument challenges a direct causative role

When your body is under physical stress, your glutathione levels can drop rapidly

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This interaction not only prompts the pituitary gland to secrete growth hormone but also suppresses somatostatin, a hormone that inhibits HGH release