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Cell death-associated DAMPs released during ferroptosis include CRT, ATP, HMGB1, and IL-33, which can promote the maturation and recruitment of antigen-presenting cells, as well as induce macrophage polarization
The 2024 Yang paper in Journal for ImmunoTherapy of Cancer documented NNMT in cancer-associated fibroblasts driving tumour progression (PMID 39067875)
The metabolic shift is underway
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Daily oral administration of Rx B12 will effectively increase serum levels Cyanocobalamin just as monthly Vitamin B-12 injections do
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