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Furthermore, removal of patient participant works reduced the overall age range of participants included in studies

Cannabis clinical trial participant data was derived from peer-reviewed literature, which introduces publication bias

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Metabolism of THC occurs primarily in the liver through cytochrome P450 enzymes, in particular CYP2C9, which converts 9-THC into 11-OH-9-THC (often referred to simply as 11-hydroxy-THC)