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No tobacco or cannabis use Results People in groups A and B (with an early onset of tobacco only, or both cannabis and tobacco) had higher rates of psychotic symptoms at age 18, with odds ratios (OR) of 3-4 When adjustments were made for potential confounders, the association persisted for cannabis plus tobacco, and diminished for tobacco only, with the OR dropping to 1.8, and the confidence interval crossing 1

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