In very rare individuals, especially (but not exclusively) in those with the COL1A1 p.(Arg312Cys) missense variant, spontaneous rupture of large arteries, intracranial aneurysms, and arteriovenous fistulae may occur [5,6,7, 9,10,11,12,13,14, 18,19,20,21,22,23,24,25,26]
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Studies show long-term smokers may see a temporary drop in testosterone after quitting, but levels usually rebound within a year often with better fertility and sexual health
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Older homes or properties with large trees nearby are more at risk due to root intrusion or aging pipes