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However, the clinical efficacy of these treatments is often hampered by factors such as rapid drug clearance and inadequate drug delivery to the site of arterial injury 4,5,6

453,454 Ferulic acid can improve the survival rate of copper-overloaded cells, significantly increase the expressions of SIRT1, Nrf2, SLC7A11, and GPX4, and downregulate the levels of MDA, 4-HNE and ROS

These symptoms usually subside within a few hours to a day

High resolution mass spectrometry of GSH (50 mM) in the presence of Ru(II)-OH (2 mM) were directly conducted after preparation and after incubation for 12 h

Another important factor is the presence or absence of serum (as mentioned above) and biological contamination, which has significant effect particularly on immune cells