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Similarely, a 6-month exposure of Sprague-Dawley rats to cigarette smoke significant increased ANG II levels and ACE protein expression and decreased ACE2 expression in lung tissue (Yuan et al., 2015)

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Considering that tobacco use usually starts during adolescence [ After a pilot study conducted in Baltimore, United States, we determined that each FGD would ideally be comprised of four to six participants, allowing groups to be small enough so that all members would actively interact with one another and engage in the pack sorting activity, yet large enough that the groups would reflect a diversity of opinions on the topic

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