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In addition, B2B cells showed morphological changes such as shrinkage and detachment, while T-B2B cells retained an adherent and elongated morphology (Fig

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Moreover, the graded relationship of CKD with the amount of smoking and the inverse graded relationship with years since quitting suggest the reversibility of the harmful effects of smoking on CKD

While we could not rule out a gateway effect for experimentation (Ever Cig clusters), its important to note that the remaining association is the upper limit of what a gateway could possibly be: in reality, since there were other common liability factors that were not captured, the remaining association is at least partly due to these other factors, so a true gateway effect is weaker than this to an unknown degree

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