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SURMOUNT-5 was a 72-week, open-label, Phase 3b randomised trial of 751 adults with obesity but without diabetes, comparing maximum-tolerated tirzepatide (10 or 15 mg) against maximum-tolerated semaglutide (1.7 or 2.4 mg)

Carlat Verdict: The GLP-1 agonists are potential game changers for the treatment of antipsychotic weight gain

10 GLP-1 clinics in Chattanooga are currently accepting new patients

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Experimental investigations have demonstrated that cholangiocytes are sensitive to GLP-1 and respond with augmented proliferation, potentially increasing the risk of duct obstruction [47,48]