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In RAW 264.7 murine and THP1 human macrophage cell lines, treatment with arsenic trioxide resulted in decreased expression of target genes of the liver X receptor/retinoid X receptor (LXR/RXR) transcription factor complex, leading to reduced cholesterol efflux (198), promoting the development of foam cells and atherogenic plaques

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The engines also have a unique fuel priming system incorporating two Holley electric pumps for getting fuel to motors quickly

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The entire focus of Little Alchemy is on the games alchemy mechanic, so it doesnt have room for any characters