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Contraindications may include a personal or family history of medullary thyroid carcinoma, Multiple Endocrine Neoplasia syndrome type 2, a history of pancreatitis, and other conditions

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Because GLP-1 medications can suppress your thirst, it is vital to drink fluids consistently throughout the day, even if you do not feel thirsty, to prevent your blood pressure from dropping too low

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However, the capacity of intrinsic antioxidant systems is not always sufficient to prevent damage caused by excessive accumulation of ROS