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Pattern recognition receptors (PRRs) play a critical role in the proper functioning of the innate immune system 37) , directly recognizing specific molecular structures, such as pathogen-associated molecular patterns (PAMPs), from microbial pathogens and DAMPs released from host cells upon damage or death

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Theres a way of measuring the pain level called the Schmidt Sting Pain Index, created by entomologist Justin Schmidt, who allowed stinging insects of all types to sting him so he could document the experience