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Annual Cost Projections 18-Month Treatment (Typical): Low-Cost All-Inclusive ($349): $349 18 = $6,282 total Straightforward and predictable Mid-Range All-Inclusive ($499): $499 18 = $8,982 total Still predictable, more expensive Hidden Fee Model ($299 advertised): Actual monthly: $448 $448 18 = $8,064 total Higher than advertised Tiered Model ($299-$499): Average monthly: $450 $450 18 = $8,100 total Unpredictable month-to-month 24-Month Treatment (Extended): Low-Cost ($349): $349 24 = $8,376 total Mid-Range ($499): $499 24 = $11,976 total Hidden Fee Model: $448 24 = $10,752 total Savings with low-cost provider over 24 months: vs

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The honest conversation: Mounjaro is a long-term or indefinite treatment for a chronic condition (obesity or diabetes)

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Last reviewed: June 12, 2026 Last updated: June 12, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations