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Animal experiments Four-week-old male BALB/C nude mice were purchased from the animal center of Changsheng Biotechnology (Liaoning, China), and kept in a specific pathogen-free condition and randomly divided into groups

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136 Overexpression of the iron-sulfur cluster assembly enzyme can prevent dihydroartemisinin-induced ferroptosis by controlling iron metabolism, raising GSH levels, and preserving mitochondrial function