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The symptoms of a vitamin B-12 deficiency may include: Fatigue, weakness Memory loss Depression Confusion Insomnia Shortness of breath Poor sense of balance Vision problems Diarrhoea or constipation Loss of appetite Cognitive functioning problems Beefy, red, smooth and sore tongue Sore mouth and/or bleeding gums Numbness and tingling of hands and feet Loss of hearing and tinnitus Pale, possibly yellowish pallor in light-skinned individuals

Shi K, Zhang G, Fu H, Li XM, Gao Y, Shi R, Xu HY, Li Y, Guo YK, Yang ZG

Levels of exendin-4 appearing in the plasma of anaesthetised rats after administration either via the intestine in the Axcess formulation (25 g per animal), or i.v