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Current evidence supports the dopaminergic hypothesis as one of the pathophysiological hypotheses for negative symptoms in SCZ, which proposes that positive symptoms are the result of overactive dopaminergic neurotransmission in the limbic pathway, whereas negative symptoms are thought to be caused by low dopaminergic function in the frontal lobes and other limbic structures of the midbrain 7,43

Although these measures may appear restrictive, they are necessary not only to protect childrens health but also their fundamental rights to health and to be protected from harmful drugs and exploitation

It is likely that more adults exceed the new guidelines, considering they are considerably more conservative

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Exposure to Nicotine and Selected Toxicants in Cigarette Smokers Who Switched to Electronic Cigarettes: A Longitudinal Within-Subjects Observational Study