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Research indicates that this compound was originally developed at the University of Arizona in the 1980s as a research compound specifically designed for investigating melanogenesis pathways and UV protection mechanisms in laboratory settings

Remarkably, the animals later performed as well as rested mice in a memory task, despite having stayed awake

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Naturally, a number of engineering techniques have been established to produce engineered EXOs with improved efficacy and sensitivity (Choi et al., 2025)

doi: 10.1016/j.celrep.2016.07.027