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This insight is translationally valuable as nicotine-induced alterations in explore/exploit processes likely also have implications for the everyday life of smokers, particularly as they can increase vulnerability for addiction to other drugs of abuse and for behavioral disorders such as pathological gambling that rely on value-based decisions 7,59 and present a high comorbidity with tobacco addiction 60

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On the contrary, our findings of a unique excess mortality risk associated with menthol flavouring in cigarettes provide additional scientific evidenceapart from their known impacts on initiation and cessationin support of the menthol flavour regulation in the USA and in [low- and middle-income countries]. Mentholnaturally found in peppermint or made in a labmakes tobacco products even more addictive and harder to quit