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Patients were monitored for a maximum of 24 months from treatment initiation until the initial diagnosis of a neuropsychiatric outcome, death, loss to follow-up, or end of study

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Injecting in the same spot repeatedly can cause irritation and make the skin more prone to developing a rash

Substantial weight loss can increase the risk of cholelithiasis Exclude organic causes of obesity (e.g., hypothyr oid ism) before prescribing Orlistat Patients should be advised to adhere to dietary guidelines