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WHO/NHD/00.10

The search terms included "UC," "smoking," "cigarettes," "mitigation," and "prevention." The reference lists, relevant reviews, and meta-analyses of all eligible articles were searched to prevent the omission of any relevant studies.The complete search strategy details can be found in Supplement 1

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In an attempt to counteract this depletion, cells exposed to cigarette smoke will increase the expression of enzymes involved in the biosynthesis of new GSH (GCLM and GCLC) and the recycling of GSSG to GSH (GSR)