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Graphical abstract Keywords: Smokeless tobacco, Pregnancy, Ovarian morphology, Hormones, Reproduction Highlights Smokeless tobacco use can lead to impairments of ovarian function, morphology, oocyte quality and hormonal regulation

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Mutual fund managers Oppenheimer Funds, BlackRock, Eaton Vance, Dreyfus, Nuveen and Goldman Sachs Asset Management all bought Puerto Ricos turbo CABs, according to a Merrill Lynch pitch document