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By integrating these mechanisms into a single conceptual framework, we aim to clarify the potential role of smoking-related exposures in shaping the synovial-cartilage microenvironment and to highlight key directions for future OA-specific mechanistic and translational research

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You might have gum disease if you experience the following: Red or swollen gums Bleeding gums Painful chewing Loose teeth Sensitive teeth Gums that are pulling away from the teeth Anyone can develop gum disease simply by allowing plaque and bacteria to get under the gums