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In this metabolic pathway, G6PD supplies reducing energy to red blood cells (RBCs) through NADPH and glutathione (GSSG), which can protect RBCs from oxidative stress
Mechanistically, high glycolysis of MDMs expressing GLUT1 drives histone Kla, which further promotes IL-10 production and subsequently induces T-cell suppression, ultimately exacerbating GBM progression
Free radical metabolism in human erythrocytes
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