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Tobacco Harm Reduction (THR) represents one of the most promising global public health policies: to encourage adult smokers who would otherwise continue to smoke to transition to less harmful products that deliver nicotine, but with fewer and substantially lower levels of toxicants associated with burning tobacco

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Semin Hematol 37(1):15-29, 2000

Nicotine is named after the tobacco plant Nicotiana tabacum, which in turn is named after Jean Nicot de Villemain, who sent tobacco and seeds to Paris in 1560, presented it to the French King, and who promoted their medicinal use