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This association suggests that bacterial infections, as evidenced by antibiotic use, may contribute to manic episodes through immune activation, highlighting infection prevention and treatment as potential targets

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L-cysteine supplementation upregulates glutathione (GSH) and vitamin D binding protein (VDBP) in hepatocytes cultured in high glucose and in vivo in liver, and increases blood levels of GSH, VDBP, and 25-hydroxy-vitamin D in Zucker diabetic fatty rats

Furthermore, donor-dependent rises in Enterobacteriaceae , alongside reductions in protective taxa Christensenellaceae and Akkermansiaceae were found (Fournier et al., 2023)