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Electrophysiological recordings of TH + neurons in the VTA of mouse brain slices revealed that IL-13 significantly reduced their firing rate, and this effect required IL-13R1

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The same review also found that in countries that had banned tobacco advertising the ban was followed by a fall in smoking on a scale which cannot reasonably be attributed to other factors

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These capture devices (effective but expensive to install everywhere), and other actions that can slow the mass migration of cigarette butts into the environment, are considered to be downstream solutions, but Gordon, at Upstream, thinks they arent up to the sheer scope of the problem