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Jansen and colleagues [22] (see Table 1) recently demonstrated that among current smokers the number of cigarettes smoked per day was consistently the strongest risk factor relative to the development of chronic cough, chronic phlegm, wheeze, and dyspnea respectively

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It in general has the construction of an inexpensive cooler, with relatively flimsy plastic hinges, plastic handles that feel like they could break under a heavy load (this is mentioned in many online user reviews), and a latchless, press fit lid