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Weight Cycling Okay some of the theory behind using pioglitazone and GLP1s to aid in fat redistribution may rest on the concept of weight cycling, which is the idea that repetitively gaining and losing weight in a cyclic pattern may benefit fat redistribution

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It achieved 16.2% weight loss at 52 weeks, with monthly or less frequent dosing

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Despite being recognized for its durability in terms of weight loss and diabetes remission [29, 39, 40], DPB-DS constitutes only 2.2% of bariatric surgeries performed worldwide [41]