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Hydration felt almost immediately

The Banting Memorial Lecture 1975

Due to the rapid proliferation and metabolism of tumor cells, glycolysis is highly active, and the tumor microenvironment (TME) often exhibits characteristics of hypoxia and glucose deprivation

If you are drawing 60 units from a 40 mg/mL vial, something is almost certainly wrong unless you have a very specific and carefully monitored protocol from your prescriber