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A future challenge in this work will be to test different reaction conditions and virus modifications in order to: (1) broaden the types of metal nanoparticles that may be produced during this process, (2) improve the reaction kinetics and (3) develop new approaches for directed metallization of viruses under neutral, non-hazardous, room temperature conditions

Fever should be avoided, as it increases cerebral metabolic demand and affects ICP

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Smoking also increases joint pain, like arthritis