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A 2022 JAMA study on 338 adults who had overweight or obesity found that taking semaglutide and liraglutide, respectively, led to an average 15.8% and 6.4% loss in body weight over 68 weeks

Oxidative stress data were analyzed by two-way ANOVA with repeated measures

A pragmatic monitoring approach checking total testosterone, free testosterone, SHBG, and haematocrit at baseline and at 36 months following any significant change in either treatment is advisable

The Basket Trials Inside TRIUMPH-1 TRIUMPH-1 randomized 2,339 adults with obesity (no diabetes) 1:1:1:1 to retatrutide 4 mg, 9 mg, 12 mg, or placebo, dosed once weekly for 80 weeks

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