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Glia 48:179182 Zhao W, Beers DR, Henkel JS et al (2010) Extracellular mutant SOD1 induces microglial-mediated motoneuron injury

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6.3 Fecal microbiota transplantation FMT, an emerging microbial-based therapeutic strategy, involves the transfer of fecal microbial communities from healthy donors into the intestinal tract of patients to restore gut microbiota homeostasis (113)

This shift results in NAD + depletion, lactate buildup, and a decrease in the intracellular pH, negatively impacting cellular function

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